Postdoc in Directed Enzyme Evolution of C1 metabolism - Copenhagen, Danmark - American Chemical Society

    American Chemical Society
    American Chemical Society Copenhagen, Danmark

    for 2 uger siden

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    Temporary
    Beskrivelse

    The Center for Biosustainability (CFB) at DTU (Denmark) and the FEMSA Biotechnology Center (CBF) at Tecnológico (TEC) de Monterrey (Mexico) have launched a joint research program to foster a bilateral strategic partnership to promote innovative projects in biosustainability (Joint CFB-CBF research program).

    The Computational Protein Engineering (CPE) group at DTU Biosustain and the Molecular and Systems Bioengineering (MSB) group at TEC campus Guadalajara (Jalisco) are offering one postdoctoral position as part of this Joint CFB-CBF program in the area of in vivo enzyme evolution in yeast for C1 metabolism. The candidate will be hired at DTU but It is required that the candidate makes at least a six month stay in the Tecnológico de Monterrey Campus Jalisco, Mexico.

    Responsibilities and qualifications
    We are looking for a colleague who is independent, will thrive within an interdisciplinary environment at two world-class research centres in Denmark and Mexico (short-term research visit at TEC for 6 months), and is highly motivated to develop novel biosustainable solutions using cutting-edge research approaches.

    Responsibilities:

    Engineer yeast strains to assimilate C1 feedstocks. Perform genome mining to identify enzyme candidates using bioinformatic approaches. Characterize enzyme variants using biophysical and biochemical methods. Generate and analyze large enzyme mutant datasets using in vivo directed evolution tools and next-generation sequencing. Implement adaptive laboratory evolution (ALE) campaigns using automation. Report your research results in peer-review scientific publications and international conferences. Collaborate within the CPE and MSB research groups and across DTU and TEC network. Qualifications:

    PhD in biotechnology, biochemistry, biology, chemistry, biophysics, or related area. Experience with yeast genetics, molecular biology, and bioinformatics. Basic programming skills in Python or similar languages. Excellent written and oral English proficiency. Excellent communication skills for working within an interdisciplinary research team. Strong analytical skills and ability to work independently. Preferred qualifications (not mandatory):

    A strong publication record in peer-review scientific journals. Experience with grant and patent writing as well as teaching. Experience with protein and metabolic engineering. Experience with directed evolution and adaptive laboratory evolution (ALE). Interest in learning automation, robotics, and machine learning to improve protein function. Interest in entrepreneurship to make a positive impact on planetary and human health. We offer
    DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

    Salary and terms of employment
    The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

    The period of employment is 2 years. The preferred starting date is July 1st, 2024, or according to our mutual agreement. The position is full time.

    You can read more about cargac@

    Dr. J. Donato García-García (JDGG):

    Google Scholar profiles:

    CAR: citations?hl=en&user=yZDS88IAAAAJ

    JDGG: citations?user=I2SY3y8AAAAJ

    More information about the organizations:

    DTU Biosustain and the Computational Protein Engineering group:

    research/research-groups/computational-protein-engineering-carlos-acevedo-rocha

    TEC de Monterrey and the Molecular and Systems Bioengineering (MSB) group:

    vivo-tec/display/PID_479677

    If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

    Application procedure
    Your complete online application must be submitted no later than 5 May :59 Danish time) .

    Apply at: Postdoc in Directed Enzyme Evolution of C1 metabolism

    Applications must be submitted as one PDF file containing all materials to be given consideration.